structural-biology.com
Evidence

Every figure, with its source.

Every headline figure on this site, with the API that verified it, the method, the time of verification and the items counted.

8 verified figures

Public PDB structures 79 Peer-reviewed papers 59 Citations 3,068 Articles 144 Patent publications 8 Clinical-stage compounds 2 Public GitHub repositories 38 Live web apps 20

shared/kpi.json last written 2026-11-04T22:26:50Z

Private work is never counted: confidential Incyte and Pfizer structures, internal programmes and private repositories are all excluded.

Public PDB structures: 79

verified 4 Nov 2026
Subline
depositor or citation author
Source
RCSB Search and Data APIs, with Marc's curated list
Method
Union of six sources (Section 4.3.2): RCSB depositor and primary-citation searches, the curated pdb-lite list, verified paper DOIs and manual additions. Every ID must be a released public RCSB entry. Private Incyte and Pfizer structures are never counted.
Items counted
79
EntryTitleRole SourcesReleased
10PI JAK1 kinase (JH1 domain) in complex with povorcitinibcitation_author b,d 10 Jun 2026
10PJ JAK2 kinase (JH1 domain) in complex with povorcitinibcitation_author b,d 10 Jun 2026
13GK CDK2 in complex with INCB125496citation_author b 30 Sep 2026
1EVS CRYSTAL STRUCTURE OF HUMAN ONCOSTATIN Mboth a,b,d 13 Sep 2000
1VLQ Crystal structure of Acetyl xylan esterase (TM0077) from Thermotoga maritima at 2.10 A resolutioncitation_author b,d 24 Aug 2004
2ETS CRYSTAL STRUCTURE OF A BACTERIAL DOMAIN OF UNKNOWN FUNCTION FROM DUF1798 FAMILY (MW1337) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS AT 2.25 A RESOLUTIONcitation_author c,d 8 Nov 2005
2EVR CRYSTAL STRUCTURE OF A PUTATIVE GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE (NPUN_R0659) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.60 A RESOLUTIONcitation_author b,d 22 Nov 2005
2FG0 Crystal structure of a putative gamma-d-glutamyl-l-diamino acid endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.79 A resolutioncitation_author b,d 10 Jan 2006
2GHR Crystal structure of homoserine o-succinyltransferase (NP_981826.1) from Bacillus cereus ATCC 10987 at 2.40 A resolutioncitation_author c,d 11 Apr 2006
2GLZ Crystal structure of a formylmethanofuran dehydrogenase subunit e-like protein (dhaf_2992) from desulfitobacterium hafniense dcb-2 at 1.45 A resolutioncitation_author b,d 18 Apr 2006
2GVI Crystal structure of a putative formylmethanofuran dehydrogenase subunit e (ta1109) from thermoplasma acidophilum at 1.87 A resolutioncitation_author b,d 13 Jun 2006
2GVK Crystal structure of a dye-decolorizing peroxidase (DyP) from Bacteroides thetaiotaomicron VPI-5482 at 1.6 A resolutioncitation_author b,d 16 May 2006
2H1T Crystal structure of a duf1089 family protein (pa1994) from pseudomonas aeruginosa at 1.80 A resolutioncitation_author b,d 30 May 2006
2HAG Crystal structure of a putative dyp-type peroxidase protein (so_0740) from shewanella oneidensis at 2.75 A resolutioncitation_author b,d 8 Aug 2006
2HBW Crystal structure of a putative endopeptidase (ava_3396) from anabaena variabilis atcc 29413 at 1.05 A resolutioncitation_author b,d 8 Aug 2006
2HUJ Crystal structure of a protein of uknown function (NP_471338.1) from Listeria innocua at 1.74 A resolutioncitation_author c,d 8 Aug 2006
2IAY Crystal structure of a duf1831 family protein (lp2179) from lactobacillus plantarum at 1.20 A resolutioncitation_author b,d 10 Oct 2006
2ICH CRYSTAL STRUCTURE OF A PUTATIVE ATTH (NE1406) FROM NITROSOMONAS EUROPAEA AT 2.00 A RESOLUTIONcitation_author b,d 3 Oct 2006
2IIZ Crystal structure of putative melanin biosynthesis protein TyrA with bound heme (NP_716371.1) from Shewanella Oneidensis at 2.30 A resolutioncitation_author b,d 14 Nov 2006
2OOC Crystal structure of Histidine Phosphotransferase ShpA (NP_419930.1) from Caulobacter crescentus at 1.52 A resolutioncitation_author b,d 6 Feb 2007
2OOK Crystal structure of a protein with unknown function (YP_749275.1) from Shewanella Frigidimarina NCIMB 400 at 1.80 A resolutioncitation_author b,d 6 Feb 2007
2PV7 Crystal structure of chorismate mutase / prephenate dehydrogenase (tyrA) (1574749) from Haemophilus influenzae RD at 2.00 A resolutioncitation_author b,d 22 May 2007
2Q3L CRYSTAL STRUCTURE OF AN UNCHARACTERIZED PROTEIN FROM DUF3478 FAMILY WITH A SPOIIAA-LIKE FOLD (SHEW_3102) FROM SHEWANELLA LOIHICA PV-4 AT 2.25 A RESOLUTIONcitation_author b,d 12 Jun 2007
2Q8U CRYSTAL STRUCTURE OF MRE11 FROM THERMOTOGA MARITIMA MSB8 (TM1635) AT 2.20 A RESOLUTIONcitation_author b,d 26 Jun 2007
2QTP Crystal structure of a duf1185 family protein (spo0826) from silicibacter pomeroyi dss-3 at 2.10 A resolutioncitation_author b,d 21 Aug 2007
2RA9 Crystal structure of a duf1285 family protein (sbal_2486) from shewanella baltica os155 at 1.40 A resolutioncitation_author b,d 16 Oct 2007
2RE3 CRYSTAL STRUCTURE OF a DUF1285 family protein (SPO_0140) FROM SILICIBACTER POMEROYI DSS-3 AT 2.50 A RESOLUTIONcitation_author b,d 9 Oct 2007
3B77 Crystal structure of a ph domain containing bacterial protein (exig_2160) from exiguobacterium sibiricum 255-15 at 2.42 A resolutioncitation_author b,d 13 Nov 2007
3BOS Crystal structure of a putative dna replication regulator HDA (SAMA_1916) from Shewanella amazonensis sb2b at 1.75 A resolutioncitation_author b,d 15 Jan 2008
3BY7 CRYSTAL STRUCTURE OF A PROTEIN STRUCTURALLY SIMILAR TO SM/LSM-LIKE RNA-BINDING PROTEINS (JCVI_PEP_1096686650277) FROM UNCULTURED MARINE ORGANISM AT 2.60 A RESOLUTIONcitation_author b,d 29 Jan 2008
3BYQ Crystal structure of a duf1185 family protein (bb2672) from bordetella bronchiseptica rb50 at 1.70 A resolutioncitation_author b,d 29 Jan 2008
3CGH Crystal structure of a susd homolog (bt_3984) from bacteroides thetaiotaomicron vpi-5482 at 1.70 A resolutioncitation_author b,d 18 Mar 2008
3CM1 Crystal structure of SsgA-like sporulation-specific cell division protein (YP_290167.1) from Thermobifida fusca YX-ER1 at 2.60 A resolutioncitation_author b,d 1 Apr 2008
3D00 Crystal structure of a tungsten formylmethanofuran dehydrogenase subunit e (fmde)-like protein (syn_00638) from syntrophus aciditrophicus at 1.90 A resolutioncitation_author b,d 20 May 2008
3DCX Crystal structure of a duf1696 family protein with a pleckstrin-homology domain (shew_0819) from shewanella loihica pv-4 at 2.00 A resolutioncitation_author b,d 29 Jul 2008
3DEE CRYSTAL STRUCTURE OF A PUTATIVE REGULATORY PROTEIN INVOLVED IN TRANSCRIPTION (NGO1945) FROM NEISSERIA GONORRHOEAE FA 1090 AT 2.25 A RESOLUTIONcitation_author b,d 5 Aug 2008
3DUE CRYSTAL STRUCTURE OF A PUTATIVE PERIPLASMIC PROTEIN FROM DUF2874 FAMILY (BVU_2987) FROM BACTEROIDES VULGATUS ATCC 8482 AT 1.85 A RESOLUTIONcitation_author b,d 5 Aug 2008
3E0F Crystal structure of a putative metal-dependent phosphoesterase (bad_1165) from bifidobacterium adolescentis atcc 15703 at 2.40 A resolutioncitation_author b,d 2 Sep 2008
3EQX CRYSTAL STRUCTURE OF A FIC FAMILY PROTEIN (SO_4266) FROM SHEWANELLA ONEIDENSIS AT 1.6 A RESOLUTIONcitation_author b,d 14 Oct 2008
3F1Z Crystal structure of putative nucleic acid-binding lipoprotein (YP_001337197.1) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 at 2.46 A resolutioncitation_author b,d 18 Nov 2008
3GF8 Crystal structure of putative polysaccharide binding proteins (DUF1812) (NP_809975.1) from BACTEROIDES THETAIOTAOMICRON VPI-5482 at 2.20 A resolutioncitation_author b,d 24 Mar 2009
3H0N Crystal structure of a duf1470 family protein (jann_2411) from jannaschia sp. ccs1 at 1.45 A resolutioncitation_author b,d 21 Apr 2009
3H41 CRYSTAL STRUCTURE OF A NLPC/P60 FAMILY PROTEIN (BCE_2878) FROM BACILLUS CEREUS ATCC 10987 AT 1.79 A RESOLUTIONcitation_author b,d 5 May 2009
3H50 CRYSTAL STRUCTURE OF A TETRACENOMYCIN POLYKETIDE SYNTHESIS PROTEIN (TCMJ) FROM XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS AT 1.60 A RESOLUTIONcitation_author b,d 5 May 2009
3HBZ Crystal structure of a putative glycoside hydrolase (bt_2081) from bacteroides thetaiotaomicron vpi-5482 at 2.05 A resolutioncitation_author b,d 26 May 2009
3HSA Crystal structure of pleckstrin homology domain (YP_926556.1) from SHEWANELLA AMAZONENSIS SB2B at 1.99 A resolutioncitation_author b,d 23 Jun 2009
3IRB Crystal structure of protein with unknown function from DUF35 family (13815350) from SULFOLOBUS SOLFATARICUS at 1.80 A resolutioncitation_author b,d 1 Sep 2009
3JXO Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritimaboth a,b,d 6 Oct 2009
3K5J Crystal structure of Putative SUFU (suppressor of fused protein) homolog (YP_208451.1) from Neisseria gonorrhoeae FA 1090 at 1.40 A resolutioncitation_author b,d 26 Jan 2010
3KK7 Crystal structure of Putative cell invasion protein with MAC/Perforin domain (NP_812351.1) from BACTERIODES THETAIOTAOMICRON VPI-5482 at 2.46 A resolutioncitation_author b,d 24 Nov 2009
3L4B Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritimaboth a,b,d 16 Feb 2010
3L5O Crystal structure of protein with unknown function from DUF364 family (ZP_00559375.1) from Desulfitobacterium hafniense DCB-2 at 2.01 A resolutioncitation_author b,d 2 Feb 2010
3M81 Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.50 A resolution (native apo structure)citation_author b,d 21 Apr 2010
3M82 Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.40 A resolution (PMSF inhibitor complex structure)citation_author b,d 26 May 2010
3M83 Crystal structure of Acetyl xylan esterase (TM0077) from THERMOTOGA MARITIMA at 2.12 A resolution (paraoxon inhibitor complex structure)citation_author b,d 12 May 2010
3NL9 Crystal structure of a putative NTP pyrophosphohydrolase (Exig_1061) from EXIGUOBACTERIUM SP. 255-15 at 1.78 A resolutioncitation_author b,d 21 Jul 2010
3O0F Crystal structure of a putative metal-dependent phosphoesterase (BAD_1165) from bifidobacterium adolescentis atcc 15703 at 1.94 A resolutioncitation_author b,d 25 Aug 2010
4G6A Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody AP33citation_author b,d 26 Sep 2012
4JM2 Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fabcitation_author b,d 29 May 2013
4JM4 Crystal Structure of PGT 135 Fabcitation_author b,d 29 May 2013
4NCO Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122citation_author b,d 13 Nov 2013
4RBO Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolutioncitation_author b,d 1 Oct 2014
5C7K Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195citation_author b,d 7 Oct 2015
5CD3 Structure of immature VRC01-class antibody DRVIA7citation_author b,d 6 Apr 2016
5CD5 Crystal structure of an immature VRC01-class antibody DRVIA7 from a Chinese donor bound to clade A/E HIV-1 gp120 corecitation_author b,d 6 Apr 2016
5SY8 Crystal structure of the complex of 10E8 Fab light chain mutant1 and T117v2 HIV-1 MPER scaffoldcitation_author b,d 8 Mar 2017
5T29 Crystal structure of 10E8 Fab light chain mutant3, against the MPER region of the HIV-1 Env, in complex with the MPER epitope scaffold T117v2citation_author b,d 8 Mar 2017
5T5B CRYSTAL STRUCTURE OF THE COMPLEX OF 10E8 FAB LIGHT CHAIN MUTANT5 AND T117V2 HIV-1 MPER SCAFFOLDcitation_author b,d 8 Mar 2017
5T6L Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2citation_author b,d 8 Mar 2017
5T80 Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidic acid (06:0 PA)citation_author b,d 8 Mar 2017
5T85 Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidylglycerol (06:0 PG)citation_author b,d 8 Mar 2017
5TFW Crystal structure of 10E8 Fab light chain mutant2 against the MPER region of the HIV-1 Env, in complex with T117v2 epitope scaffoldcitation_author b,d 8 Mar 2017
5UFV Crystal Structure of a Cellulose-active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*)both a,b,d 15 Mar 2017
6C9U Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab)citation_author b,d 23 May 2018
6OFO Crystal structure of split green fluorescent protein (GFP); s10 circular permutant (194-195)depositor a,d 10 Jul 2019
8E1X FGFR2 kinase domain in complex with a Pyrazolo[1,5-a]pyrimidine analog (Compound 29)both a,b,d 23 Nov 2022
8UV0 Discovery of (4-Pyrazolyl)-2-Aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2both a,b,d 14 Feb 2024
9E5D Discovery of an Orally Biovailable KRAS G12D Inhibitorboth a,b,d 22 Jan 2025
9E5F Discovery of an Orally Bioavailable KRAS G12D Inhibitorboth a,b,d 22 Jan 2025

Peer-reviewed papers: 59

verified 4 Nov 2026
Subline
articles, reviews and letters with a verified DOI
Source
ORCID, OpenAlex and Crossref
Method
ORCID is the primary list and OpenAlex fills gaps. Every DOI must resolve at Crossref (DataCite as fallback), its registered title must match, and its registered author list must name Deller with a given name starting M.
Items counted
59
DOITitleJournal YearVerified at
10.1002/pro.497 The crystal structure of a bacterial Sufu‐like protein defines a novel group of bacterial proteins that are similar to the N‐terminal domain of human SufuProtein Science 2010crossref
10.1002/prot.21208 Crystal structure of homoserine O ‐succinyltransferase from Bacillus cereus at 2.4 Å resolutionProteins: Structure, Function and Genetics 2007crossref
10.1002/prot.21550 Crystal structures of two novel dye‐decolorizing peroxidases reveal a β‐barrel fold with a conserved heme‐binding motifProteins: Structure, Function and Genetics 2007crossref
10.1002/prot.21673 Identification and structural characterization of heme binding in a novel dye‐decolorizing peroxidase, TyrAProteins: Structure, Function and Genetics 2007crossref
10.1002/prot.22020 Crystal structures of MW1337R and lin2004: Representatives of a novel protein family that adopt a four‐helical bundle foldProteins: Structure, Function and Genetics 2008crossref
10.1002/prot.22338 Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR‐1 at 1.6 Å resolutionProteins: Structure, Function and Bioinformatics 2009crossref
10.1002/prot.22360 Crystal structure of a novel Sm‐like protein of putative cyanophage origin at 2.60 Å resolutionProteins: Structure, Function and Bioinformatics 2009crossref
10.1002/prot.23035 Crystal structure of a metal‐dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activityProteins: Structure, Function and Bioinformatics 2011crossref
10.1002/prot.24041 Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritimaProteins: Structure, Function and Bioinformatics 2012crossref
10.1007/s10822-015-9833-8 Models of protein–ligand crystal structures: trust, but verifyJournal of Computer-Aided Molecular Design 2015crossref
10.1016/j.immuni.2016.03.006 Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese DonorImmunity 2016crossref
10.1016/j.jmb.2008.10.059 A Structural Basis for the Regulatory Inactivation of DnaAJournal of Molecular Biology 2009crossref
10.1016/j.jmb.2009.05.023 Crystal Structure of Histidine Phosphotransfer Protein ShpA, an Essential Regulator of Stalk Biogenesis in Caulobacter crescentusJournal of Molecular Biology 2009crossref
10.1016/j.jmb.2009.11.006 Bacterial Pleckstrin Homology Domains: A Prokaryotic Origin for the PH DomainJournal of Molecular Biology 2010crossref
10.1016/j.jmb.2010.01.049 Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA RepairJournal of Molecular Biology 2010crossref
10.1016/j.str.2008.12.008 Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid EndopeptidaseStructure 2009crossref
10.1016/s0959-440x(00)00072-5 Cell surface receptorsCurrent Opinion in Structural Biology 2000crossref
10.1016/s0969-2126(00)00176-3 Crystal structure and functional dissection of the cytostatic cytokine oncostatin MStructure 2000crossref
10.1021/acs.jmedchem.2c01366 Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant Fibroblast Growth Factor Receptor (FGFR) 2/3Journal of Medicinal Chemistry 2022crossref
10.1021/acs.jmedchem.3c02287 Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2Journal of Medicinal Chemistry 2024crossref
10.1021/acs.jmedchem.4c02662 Discovery of INCB159020, an Orally Bioavailable KRAS G12D InhibitorJournal of Medicinal Chemistry 2025crossref
10.1021/acs.jmedchem.5c03753 Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune DiseasesJournal of Medicinal Chemistry 2026crossref
10.1021/acs.jmedchem.6c01506 Discovery of INCB127443: A Potent and Orally Available Inhibitor of Cyclin-Dependent Kinase 2Journal of Medicinal Chemistry 2026crossref
10.1021/acs.jmedchem.6c02625 Discovery of INCB161734: A Selective Inhibitor of the KRAS G12D MutantJournal of Medicinal Chemistry 2026crossref
10.1021/acschembio.7b00016 The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide MonooxygenaseACS Chemical Biology 2017crossref
10.1021/jacs.8b02100 Structure–Function Analysis of the Extended Conformation of a Polyketide Synthase ModuleJournal of the American Chemical Society 2018crossref
10.1038/nsmb.2594 Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120Nature Structural and Molecular Biology 2013crossref
10.1073/pnas.1502855112 Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cellsProceedings of the National Academy of Sciences of the United States of America 2015crossref
10.1074/jbc.m109.018564 Structural and Functional Characterizations of SsgB, a Conserved Activator of Developmental Cell Division in Morphologically Complex ActinomycetesJournal of Biological Chemistry 2009crossref
10.1107/s1399004715013917 Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimerActa Crystallographica Section D: Biological Crystallography 2015crossref
10.1107/s1744309109018168 The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-foldActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109021988 Conformational changes associated with the binding of zinc acetate at the putative active site of Xc TcmJ, a cupin from Xanthomonas campestris pv. campestrisActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109022672 The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulationActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109022684 The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolismActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109023689 Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolismActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109025196 The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulatorActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109037749 Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolismActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109042481 Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand bindingActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109046788 The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory functionActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109050416 Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transductionActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309109050647 Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolismActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110002514 The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding roleActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110006548 A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolutionActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110007517 Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelationActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110020166 Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc fingerActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110021214 Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidasesActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110021688 The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymesActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110023055 Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicronActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110025534 Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15Acta Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110028228 Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolismActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s1744309110032999 Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding moleculesActa Crystallographica Section F: Structural Biology and Crystallization Communications 2010crossref
10.1107/s2053230x14000387 Approaches to automated protein crystal harvestingActa Crystallographica Section F:Structural Biology Communications 2014crossref
10.1107/s2053230x15024619 Protein stability: a crystallographer's perspectiveActa Crystallographica Section:F Structural Biology Communications 2016crossref
10.1126/science.1245625 Crystal Structure of a Soluble Cleaved HIV-1 Envelope TrimerScience 2013crossref
10.1128/jvi.01939-12 Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33Journal of Virology 2012crossref
10.1158/1538-7445.am2024-5900 Abstract 5900: INCB161734: A novel, potent, and orally bioavailable KRAS G12D selective inhibitor demonstrates antitumor activity in KRAS G12D mutant tumorsCancer Research 2024crossref
10.1371/journal.pone.0107309 Structural Insights into the Recognition of Phosphopeptide by the FHA Domain of KanadaptinPLoS ONE 2014crossref
10.1371/journal.pone.0122512 Crystal Structure of a Two-Subunit TrkA Octameric Gating Ring AssemblyPLoS ONE 2015crossref
10.1371/journal.ppat.1006212 Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic designPLoS Pathogens 2017crossref

Citations: 3,068

verified 4 Nov 2026
Subline
h-index 25
Source
OpenAlex Authors API
Method
cited_by_count and summary_stats.h_index for the OpenAlex author profile linked to Marc's ORCID iD.
Items counted
4
MetricValue
cited_by_count 3068
h_index 25
i10_index 41
works_count 66

Articles: 144

verified 4 Nov 2026
Subline
of 226 on marcdeller.com
Source
WordPress REST API
Method
Every post placed on this site is re-checked for status = publish on marcdeller.com; the subline is the live X-WP-Total for all posts.
Items counted
144
PostSectionOriginal
Hidden Chemistry in the Protein Data Bank: What Else Are We Missing? Field Guide marcdeller.com
How AI Is Revealing the Secret Pathways of Protein Folding Field Guide marcdeller.com
Generative AI for Protein Pocket Design: The Next Leap in Drug Discovery Field Guide marcdeller.com
Flow-Based Models: A New Paradigm for Protein Structure Generation Field Guide marcdeller.com
Compositional Protein Design: Building Proteins from 3D Ellipsoid Blueprints Field Guide marcdeller.com
Protein Structure and Redox Biology: NOS Linkages as Allosteric Switches Field Guide marcdeller.com
What If Protein Structures Could Be Designed Like LEGO? Modular Approaches in 2025 Field Guide marcdeller.com
2025 – Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor Casebook marcdeller.com
2024 – Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective CDK2 Inhibitors Casebook marcdeller.com
2022 – Discovery of Potent and Selective Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2/3 Casebook marcdeller.com
2018 – Structure–function analysis of the extended conformation of a polyketide synthase module Casebook marcdeller.com
2017 – Validation of Protein–Ligand Crystal Structure Models: Small Molecule and Peptide Ligands Field Guide marcdeller.com
2017 – Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design Casebook marcdeller.com
2016 – Key gp120 glycans pose roadblocks to the rapid development of VRC01-class antibodies in an HIV-1- infected Chinese donor Casebook marcdeller.com
2013 – Crystal structure of a soluble cleaved HIV-1 envelope trimer Casebook marcdeller.com
2013 – Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Casebook marcdeller.com
2015 – Protein stability: a crystallographer’s perspective Field Guide marcdeller.com
2017 – The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase Casebook marcdeller.com
2013 – Models of protein–ligand crystal structures: trust, but verify Field Guide marcdeller.com
Top96 Crystal Screen Field Guide marcdeller.com
Universal Mounting Robot (UMR) Field Guide marcdeller.com
Beyond the Microscope: How Cryo-ET is Revealing Disease in Its Native State Field Guide marcdeller.com
The Protein Architect: How Generative AI Is Building the Drugs of Tomorrow Field Guide marcdeller.com
Hitting the Delete Button on Disease: The Rise of Targeted Protein Degraders Casebook marcdeller.com
The Self-Driving Lab: How Automation and AI Are Redefining the Pace of Discovery Playbook marcdeller.com
Beyond Trial and Error: AI-Driven Design of Peptide Therapeutics Field Guide marcdeller.com
AI-Driven Inverse Protein Folding: Transforming Protein Design for Next-Gen Therapeutics Field Guide marcdeller.com
Cryo-EM and the New Frontier in Membrane Protein Drug Design Field Guide marcdeller.com
Beyond the Cell: The New Frontier of Extracellular Protein Degradation Casebook marcdeller.com
Building Proteins Brick by Brick: How AI Is Assembling Novel Bio-Machines Field Guide marcdeller.com
The Quantum Leap in Drug Design: Using QM/MM to Predict Perfect Fits Field Guide marcdeller.com
Beyond Inhibition: The Rise of Conditional Degraders for Safer Medicines Casebook marcdeller.com
Tiny Pipes, Big Discoveries: How Microfluidics Are Accelerating Structural Biology Field Guide marcdeller.com
The New Architects: How Generative AI Is Designing Novel Protein Scaffolds Field Guide marcdeller.com
Plastic-Eating Enzymes Decoded—PETase’s Structure and Mutation Map Casebook marcdeller.com
The Enzyme Toolbox—Alternatives to PETase for Microplastic Breakdown Casebook marcdeller.com
PETase Enzyme Therapy—A New Frontier in Medical Microplastic Removal Casebook marcdeller.com
Engineered Enzymes—Design for Safe, Targeted Microplastic Therapeutics Casebook marcdeller.com
Supercharging Discovery: How LLM Prompts Are Transforming Structural Biology and Cheminformatics Field Guide marcdeller.com
Multi-Step LLM Prompt: From Protein Sequence to Validated Protein Structure Field Guide marcdeller.com
Revolutionizing Protein Structure Analysis: Cryo-EM without Purification Accelerates the Future of Structural Biology Field Guide marcdeller.com
Alphafold Local Install on Mac Field Guide marcdeller.com
Installation of RFdiffusion on MacOSX M1 architecture without GPU support Field Guide marcdeller.com
Shedding Light on the Shadows: The Untapped Potential of the Dark Kinome Casebook marcdeller.com
Engineering Protein Stability: Unlocking the Secrets of Successful Crystallization Field Guide marcdeller.com
Revolutionizing Protein Structure Determination: How MICA Combines Cryo-EM and AlphaFold3 for Unprecedented Accuracy Field Guide marcdeller.com
Capturing the Invisible: Understanding the Ångström in Structural Biology Field Guide marcdeller.com
Unleashing Dynamic Precision: How DRGSCROLL Transforms Protein–Ligand Docking Field Guide marcdeller.com
Engineering the Future of Proteins: Unveiling the Latest AI Tools Transforming Structural Biology in 2025 Field Guide marcdeller.com
Unlocking Protein Structure Insights without a Lab: Harnessing CRO Services for Structural Biology Research Playbook marcdeller.com
Revolutionary AI Tool XenoBug Transforms Environmental Pollution Control Through Predictive Enzyme Discovery Casebook marcdeller.com
The Shape-Shifting World of Intrinsically Disordered Region Binding Proteins Casebook marcdeller.com
The LockTac Revolution: Binding the Future of Therapeutics Casebook marcdeller.com
Unveiling FragLites: Pioneering Precision in Drug Discovery Playbook marcdeller.com
Revolutionizing Drug Discovery: LatentX and the Future of Protein Binder Design Field Guide marcdeller.com
MARCUS: Revolutionizing Chemical Literature Curation with AI-Driven Annotation and Recognition Playbook marcdeller.com
Nanobodies: Revolutionizing Molecular Medicine Through Nature’s Smallest Antibodies Casebook marcdeller.com
Optimizing Data Volume and Diversity for Robust Antibody–Antigen ΔΔG Prediction Field Guide marcdeller.com
Empowering QSAR Modeling: Optimal Data Practices and Cutting-Edge Tools Playbook marcdeller.com
Revolutionizing Drug Discovery: The Click2Drug Platform and the Rise of AI-Powered Virtual Screening Field Guide marcdeller.com
2015 – Models of protein–ligand crystal structures: trust, but verify Field Guide marcdeller.com
2015 – Crystal structure of a two-subunit TrkA octameric gating ring assembly Casebook marcdeller.com
2014 – Approaches to automated protein crystal harvesting Field Guide marcdeller.com
2012 – Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33 Casebook marcdeller.com
My Work Driving Innovation in Precision Oncology Through Structure-Based Drug Design Casebook marcdeller.com
Building a Comprehensive Protein Production, X-ray Crystallography, and Cryo-EM Laboratory from Scratch Playbook marcdeller.com
JAK2-V617F and the Evolution of Targeted Therapy: Precision Medicine Transforms Myeloproliferative Neoplasm Treatment Casebook marcdeller.com
Unlocking Molecular Potential: The Evolution of Topliss Tree and Bioisosteric Strategies in Modern Drug Discovery Casebook marcdeller.com
Revolutionary Cryo-EM Breakthrough: Di-Gembodies Transform Small Protein Structure Determination Field Guide marcdeller.com
Remapping the Chemical and Pharmacological Spaces of Drugs: Navigating Tomorrow’s Therapeutic Frontier Field Guide marcdeller.com
The Memorization Trap: Have Protein-Ligand Cofolding Methods Transcended Simple Data Recall? Field Guide marcdeller.com
Revolutionizing Protein Crystallography: The Synergy of TELSAM-DARPin Fusion and Electric Field Optimization Field Guide marcdeller.com
The $40 Billion Revolution: How Bispecific Antibodies Are Transforming Cancer Care Casebook marcdeller.com
Spacial Score─A Comprehensive Topological Indicator for Small-Molecule Complexity Field Guide marcdeller.com
Precision Timing of Cytokine Signals through Facilitated Dissociation Casebook marcdeller.com
Revolutionary Bridge Between Prediction and Reality: How Elastic Networks Transform AlphaFold2’s Structural Accuracy Field Guide marcdeller.com
Protein Hunter: Pioneering the Next Frontier of AI-Driven Protein Design Field Guide marcdeller.com
The Unsung Hero: How a Single Chlorine Atom Transforms Drug Discovery Casebook marcdeller.com
TYK2 Biology: How Deep Mutational Scanning Reveals New Therapeutic Frontiers Casebook marcdeller.com
Elevating Science Communication: Effortless 3D Structure Embedding with 3Dmol.js Field Guide marcdeller.com
Unlocking Membrane Protein Structures: The Crystallization Revolution Reshaping Drug Discovery Field Guide marcdeller.com
Outrunning Diffusion: The Fast Lane in CryoEM Grid Preparation Field Guide marcdeller.com
HGMP01 and other Hidden Guardians: How the Human Gut Fights Back Against Plastic Pollution Casebook marcdeller.com
HGMP01 and FAST-PETase: Decoding Two Paths to Plastic Degradation – Engineered versus Natural PETase Enzymes Casebook marcdeller.com
Engineering Evolution: How FAST-PETase and Other Variants Are Transforming Plastic Biodegradation Casebook marcdeller.com
Unlocking the Power of Protein Engineering: FDA-Approved Enzyme Therapies Transform Rare Disease Treatment Casebook marcdeller.com
Decoding the Molecular Machinery Behind Plastic Degradation Casebook marcdeller.com
Tuning the Signal: Rational Design of G Protein Selectivity Casebook marcdeller.com
Self-Encoded Libraries: A New Era in Drug Discovery Screening Playbook marcdeller.com
Transforming Antibody Design: How Artificial Intelligence Revolutionizes Structure Prediction Field Guide marcdeller.com
Molecular Architecture of GLP-1 Receptor Drug Binding Reveals Dynamic Activation Mechanisms Casebook marcdeller.com
Discovery of an Orally Bioavailable KRAS G12D Inhibitor Casebook marcdeller.com
Discovery of an Orally Bioavailable KRAS G12D Inhibitor_2 Casebook marcdeller.com
Discovery of (4-Pyrazolyl)-2-Aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2 Casebook marcdeller.com
FGFR2 Kinase Domain in Complex with a Pyrazolo[1,5-a]pyrimidine Analog (Compound 29) Casebook marcdeller.com
Crystal Structure of [KS3][AT3] Didomain from Module 3 of 6-Deoxyerythronolide B Synthase in Complex with Antibody Fragment (Fab) Casebook marcdeller.com
Crystal Structure of a Cellulose-Active Polysaccharide Monooxygenase from M. thermophila (MtPMO3*) Casebook marcdeller.com
Crystal Structure of the Complex of 10E8 Fab Light Chain Mutant1 and T117v2 HIV-1 MPER Scaffold Casebook marcdeller.com
Crystal Structure of an Immature VRC01-Class Antibody DRVIA7 from a Chinese Donor Bound to Clade A/E HIV-1 gp120 Core Casebook marcdeller.com
Crystal Structure of BG505 SOSIP gp140 HIV-1 Env Trimer Bound to Broadly Neutralizing Antibodies PGT128 and 8ANC195 Casebook marcdeller.com
Crystal Structure of Nanog Homeodomain (NANOG) from Homo sapiens at 3.30 Å Resolution Casebook marcdeller.com
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Fab PGT122 Casebook marcdeller.com
Crystal Structure of PGT135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab Casebook marcdeller.com
Structure of the Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Region 412-423 Bound to the Broadly Neutralizing Antibody AP33 Casebook marcdeller.com
Crystal Structure of Acetyl Xylan Esterase (TM0077) from Thermotoga maritima at 2.40 Å Resolution Casebook marcdeller.com
Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly from Thermotoga maritima Casebook marcdeller.com
Crystal Structure of TrkA-N Domain Protein from Thermotoga sp. RQ2 Casebook marcdeller.com
Crystal Structure of a Putative Metal-Dependent Phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis at 1.94 Å Resolution Casebook marcdeller.com
Crystal Structure of a Putative NTP Pyrophosphohydrolase (Exig_1061) from Exiguobacterium sp. 255-15 at 1.78 Å Resolution Casebook marcdeller.com
Crystal Structure of a PH Domain Containing Bacterial Protein (Exig_2160) from Exiguobacterium sibiricum 255-15 at 2.42 Å Resolution Casebook marcdeller.com
Crystal Structure of MRE11 from Thermotoga maritima MSB8 (TM1635) at 2.20 Å Resolution Casebook marcdeller.com
Crystal Structure of Histidine Phosphotransferase ShpA (NP_419930.1) from Caulobacter crescentus at 1.52 Å Resolution Casebook marcdeller.com
Crystal Structure of a Dye-Decolorizing Peroxidase (DyP) from Bacteroides thetaiotaomicron VPI-5482 at 1.6 Å Resolution Casebook marcdeller.com
Crystal Structure of Human Oncostatin M Casebook marcdeller.com
AXIS: Closing the Loop on Crystal Detection Field Guide marcdeller.com
PETase: Nature’s Solution to a Human-Made Problem Casebook marcdeller.com
An Enzyme That Eats Plastic — Inside Your Blood Casebook marcdeller.com
When the Enzyme Is Its Own Blueprint: Protein-Templated DNA Synthesis in DRT3 PDB Pulse marcdeller.com
From Noise to Nanomolar: PXDesign’s New Benchmark for Protein Binder Design PDB Pulse marcdeller.com
When the Wet Lab Becomes the Bottleneck: Self-Driving Platforms for Protein Engineering PDB Pulse marcdeller.com
OpenBind Publishes a Dense Structure-Affinity Dataset for Structure-Based AI PDB Pulse marcdeller.com
2026 – Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases Casebook marcdeller.com
<b>AnalyzeBoltz</b>: Harvest the sprawling Boltz2 output tree, tidy summary, CSV, and CIF output folder Playbook marcdeller.com
<b>ChatMol</b>: Natural-language control of PyMOL, describe the scene, get the picture Playbook marcdeller.com
<b>cif2plip</b>: Protein-ligand interaction profiling using PLIP for co-folding outputs which produce CIF files Playbook marcdeller.com
<b>FoldForge</b>: Browser GUI for the whole Boltz-2 workflow Playbook marcdeller.com
<b>Smiles2YAML</b>: From a JSON of candidate SMILES to a folder of Boltz-2 input YAML Playbook marcdeller.com
<b>GPCR Binning</b>: Structural binning and organisation utilities for GPCR datasets Playbook marcdeller.com
<b>PocketTide</b>: An interactive dashboard for GLP-1R structures Playbook marcdeller.com
<b>Boltz2Run</b>: Every run logged, timed, and reproducible Playbook marcdeller.com
ChemSage: Vibe-Coding a Chemically Aware Drug-Discovery LLM on Local Hardware Playbook marcdeller.com
<b>ChemSage</b>: A hybrid, chemically aware LLM for drug discovery: RAG for facts, a QLoRA-tuned model for behavior Playbook marcdeller.com
BoltzMaker: Vibe-Coding a Campaign-Scale Boltz-2 Pipeline Playbook marcdeller.com
<b>BoltzMaker</b>: Boltz2 campaign-scale structure and affinity prediction, and binding analysis Playbook marcdeller.com
<b>AlphaFraud</b>: Weekly watcher: newly deposited human PDB structures vs their blind AlphaFold predictions — a running test of whether protein folding is solved Playbook marcdeller.com
<b>ChatPDB</b>: A protein-structure-literate AI assistant for the Protein Data Bank: RAG for facts, a QLoRA-tuned model for behaviour Playbook marcdeller.com
<b>FlexAppeal</b>: An OpenMM-powered molecular dynamics pipeline: submit a protein, run it, watch its flexibility unfold Playbook marcdeller.com
<b>TopPDBLX</b>: Every PDB crystallisation condition, parsed and indexed against his own JCSG Top96 taxonomy Playbook marcdeller.com
<b>PANTS</b>: Mines metagenomes for uncharacterised PETase and MHETase candidates, ranked by catalytic triad and oxyanion hole Playbook marcdeller.com
<b>CODSWALLOP</b>: Every PDB entry for a protein family: what was made, what it bound, what crystallised Playbook marcdeller.com
<b>ButtFold</b>: A protein folds in your browser and the trajectory becomes music: PhoneFold’s web sibling Playbook marcdeller.com
<b>ALPHABETTI</b>: A protein sequence logo in 3D, wrapped around its own ESMFold-predicted structure Playbook marcdeller.com
<b>GOBSMACKED</b>: fold, dock, relax and annotate a protein-ligand complex, then grade it against the real crystal structure Playbook marcdeller.com
<b>FAFFAbout</b>: A small LLM trained on the PSI TargetTrack archive, forecasting which targets crystallise and which fail Playbook marcdeller.com

Patent publications: 8

verified 4 Nov 2026
Subline
distinct publication numbers
Source
Google Patents structured metadata
Method
Seeded from the publication numbers in Marc's Patents posts and re-harvested each run. Each number must return HTTP 200 at patents.google.com and list a DC.contributor inventor named Marc Deller.
Items counted
8
Publication numberTitle Inventor matchedWrite-up
US20250333420A1 Fused bicyclic pyrimidones as wrn inhibitors Marc Deller marcdeller.com
US20260098041A1 Fused bicyclic pyrimidones as wrn inhibitors Marc Deller marcdeller.com
US20250333419A1 Bicyclic compounds as inhibitors of wrn Marc Deller marcdeller.com
US20250270217A1 Imidaz0[1,2-a]pyrimidine-5(1 h)-ones having a covalent warhead at the 3-position as wrn inhibitors Marc Deller marcdeller.com
US20250270218A1 Imidaz0[1,2-a]pyrimidine-5(1 h)-ones as wrn inhibitors Marc Deller marcdeller.com
WO2023107994A1 Anti-mutant calreticulin (calr) antibodies and uses thereof Marc C. DELLER marcdeller.com
US20250215006A1 Tricyclic compounds as inhibitors of wrn Marc D. Deller marcdeller.com
US20250236622A1 Bicyclic compounds as inhibitors of wrn Marc Deller marcdeller.com

Clinical-stage compounds: 2

verified 4 Nov 2026
Subline
subjects of Marc's papers with registered studies
Source
ClinicalTrials.gov API v2, with ChEMBL synonyms
Method
Candidate names come from INN stems and company codes in the titles of verified papers Marc co-authored. Synonyms are resolved with ChEMBL. A candidate counts only when ClinicalTrials.gov returns at least one study for its name or a synonym. Comparator and ligand-only mentions never count.
Items counted
2
Rejected
3
CompoundStudiesPhases NCT IDsPaper
povorcitinib 25 PHASE1, PHASE2, PHASE3 NCT03569371, NCT03607487, NCT04476043, NCT04818346, NCT05061693, NCT05068466 and 14 more DOI
INCB161734 6 PHASE1, PHASE3 NCT07853040, NCT07018635, NCT06179160, NCT07522073, NCT07814404, NCT07854249 DOI
3 candidates not counted
INCB127443 no registered study on ClinicalTrials.gov
INCB159020 no registered study on ClinicalTrials.gov
INCB054707 same compound as povorcitinib, counted once

Public GitHub repositories: 38

verified 4 Nov 2026
Subline
8 stars
Source
GitHub REST API
Method
Account verified by profile field(s) name, blog. Counts public repositories owned by bellcheddar with fork = false (archived ones still count); the subline sums stargazers_count. Private repositories are never counted.
Items counted
38
RepositoryDescription LanguageStarsLast push
NOBBLE Neosubstrate and Oligopeptide Binder Benchmarking for Ligase Engagement: scores peptide poses against targeted-protein-degradation machinery with Boltz-2 ternary co-folding, benchmarked against 285,996 observed small-molecule bridges. Python 0 2026-11-04
DEBRIS Every DOI-verified paper that puts a plastic particle inside a human disease, tagged by a fine-tuned 3B model and mapped. Live at debris.mdeller.com Python 0 2026-11-01
BINMAN Blind-spot INventory of Molecular Adhesives and Neosubstrates: an empirical atlas of bridging ligands, structural degrons, E3 ligase triage and degradability Python 0 2026-10-17
FlexAppeal Prepare OpenMM molecular dynamics runs and analyse the results: a guided input wizard, a self-contained run bundle for your own machine, and interactive trajectory analysis Python 0 2026-10-14
FAFFAbout Fine-tuned Attrition Forecasting From Archives: where will your protein die? Grounded in 335k PSI TargetTrack attempts Python 0 2026-09-28
chatMCD Ask a question about Marc C. Deller and get a straight answer, drawn from his own writing. Retrieval-grounded chatbot: Flask + Hugging Face ZeroGPU + WordPress plugin. Python 0 2026-09-17
GATECRASHER Interactive dashboard walking through four structure-based drug discovery campaigns: the pocket, the SAR, the edits and the structural basis of selectivity Python 0 2026-09-15
PUNT Play-by-play, Uproar, Numbers & Trash-talk: a mobile-first fantasy football companion for a ten-team bar league, built on ESPN's undocumented fantasy API Python 0 2026-09-14
GOBSMACKED Fold, dock, relax and annotate a protein-ligand complex, then check it against the experimental structure. Python 1 2026-09-10
ButtFold A protein folds in your browser and the trajectory becomes music. The web version of PhoneFold: a structure-based Go model in WebAssembly, sonified note-for-note the same as the Apple app. JavaScript 0 2026-09-09
ALPHABETTI A protein sequence logo in 3D, wrapped around its own predicted structure. Amino acid letters stacked by how strongly a language model expects them, with no multiple sequence alignment anywhere. Python 0 2026-09-05
BoltzMaker BoltzMaker: Boltz2 campaign-scale structure and affinity prediction, binding analysis, and run control, orchestrated end to end from a single spec file. Python 2 2026-09-02
PhoneFold A Swift app that folds a protein on the Apple Neural Engine and turns the trajectory into music. iPhone, iPad, Mac, Watch, Vision Pro. Swift 0 2026-09-01
HAWKER Mines the graveyard of failed clinical assets for reclaimable drugs, reusable pockets and under-exploited targets. Multiplatform SwiftUI, live public APIs, no hand curation. Swift 0 2026-08-28
JUMPjetANE Vertical take-off molecular dynamics: UniProt ID in, conformational movie out. On-device crude torsional Monte Carlo with jump analytics, for iOS and iPadOS. Swift 0 2026-08-27
PfamIE The entire Pfam universe as an on-device inference engine: paste a sequence, get a family, offline. Swift/SwiftUI for iOS, iPadOS, macOS, visionOS and watchOS. Swift 0 2026-08-27
BOFFIN BOFFIN: Boundary, Order, Fitness and Family INference. On-device protein sequence analysis on the Apple Neural Engine plus an interactive structure viewer, for iOS and iPadOS. Swift 0 2026-08-27
CODSWALLOP Family-centric structural biology: every PDB entry for a protein family, cross-referenced in ninety seconds. Constructs, ligands, methods, resolutions and coverage in one interactive drawer. Python 0 2026-08-12
TopPDBLX Parsed, normalised and sequence-linked database of crystallisation conditions from the Protein Data Bank Python 1 2026-08-12
PANTS PETase ANnotation and Triage System: discover, triage and engineer PET-degrading enzymes for therapeutic use at 37 C, not industrial use at 70 C. Python 0 2026-08-08
AlphaFraud Catch AlphaFold where the fold is wrong: weekly, automatically, on freshly deposited human structures. Python 0 2026-08-05
chatPDB A protein-structure-literate AI assistant for the Protein Data Bank: RAG + QLoRA fine-tune + live Biopython/gemmi/DSSP/PyMOL tool calls, local on Apple Silicon with MLX-LM. Python 1 2026-07-24
ChemSage A hybrid, chemically aware LLM for drug discovery: RAG for facts, QLoRA fine-tuned model for behaviour, and live RDKit/PyMOL tool calls. Runs locally on Apple Silicon via MLX-LM. HTML 0 2026-07-24
PocketTide Dashboard for GLP-R1 Structures HTML 0 2026-06-15
microplastic-blaster-editor Editor for MicroPlastic Blaster game development JavaScript 0 2026-06-15
gpcr-binning no description Promela 0 2026-06-15
FoldForge GUI for generation of Boltz2 input YAML files and run commands HTML 0 2026-06-15
smiles2grid Render SMILES extracted from a JSON file into a single PDF with boxed 5x5 grids using RDKit and ReportLab Python 0 2026-06-15
wordpressID Bash command to return Wordpress ID, page type, and Title — 0 2026-06-15
SiteHealthInspector Comprehensive script to probe timing metrics, https status, cache, CDN headers, security, SSL/TLS, complression, DNS, CMS, overall health Shell 0 2026-06-15
analyze-boltz2-results A post-run analysis script for Boltz-2 co-folding predictions. Python 0 2026-06-15
generate_yaml A command-line utility for generating Boltz-2 / co-folding input YAML files from a batch of candidate SMILES stored in a JSON file. Python 0 2026-06-15
simple-zsh-script-to-run-boltz2 A minimal, production-ready shell wrapper for running Boltz-1/Boltz-2 structure predictions from the command line. Handles logging, runtime tracking, and input sanitisation automatically so every run is reproducible and auditable. Shell 0 2026-06-15
microplastic-blaster A browser-based arcade game by Elora Therapeutics — the biotech developing first-in-class enzyme therapy to remove microplastics from the human body. Fire enzymatic blasts at incoming polymer particles, protect the cell, and climb the global leaderboard. HTML 0 2026-06-15
cif2plip Converts Boltz output CIF to standardized PDB and then runs PLIP to analyze protein-ligand interactions and produce Pymol session file. Python 1 2026-06-15
site-doctor A single-file, dependency-free Python 3 tool that diagnoses the health, content, and SEO/performance profile of a WordPress site using only the standard library. Python 0 2026-06-15
chatRDKit Natural-language chat frontend for RDKit, powered by a local Ollama model Python 1 2026-06-15
chatmol Natural-language chat frontend for PyMOL, powered by a local Ollama model Python 1 2026-06-15

Live web apps: 20

verified 4 Nov 2026
Subline
of 20 listed
Source
Direct HTTP checks of every URL in apps.json
Method
GET each app URL with a 10 s timeout; HTTP 200 counts as live.
Items counted
20
AppURLStatus
DEBRIS https://debris.mdeller.com live
BINMAN https://binman.mdeller.com live
NOBBLE https://nobble.mdeller.com live
PODIUM https://podium.mdeller.com live
FAFFAbout https://faffabout.mdeller.com live
GATECRASHER https://gatecrasher.mdeller.com live
PUNT https://punt.mdeller.com live
chatMCD https://chatmcd.mdeller.com live
GOBSMACKED https://gobsmacked.mdeller.com live
ALPHABETTI https://alphabetti.mdeller.com live
ButtFold https://buttfold.mdeller.com live
CODSWALLOP https://codswallop.mdeller.com live
TopPDBLX https://toppdblx.mdeller.com live
FlexAppeal https://flexappeal.mdeller.com live
AlphaFraud https://alphafraud.mdeller.com live
BoltzMaker https://boltzmaker.mdeller.com live
ChatPDB https://chatpdb.mdeller.com live
ChemSage https://chemsage.mdeller.com live
MicroPlastics Blaster https://mdeller.com/game/microplastic_blaster_115.html live
PANTS https://pants.mdeller.com live