5CD3: Structure of immature VRC01-class antibody DRVIA7
X-ray · 2.90 Å · released 6 Apr 2016 · Homo sapiens
How it was solved
- Method
- X-ray
- Resolution
- 2.90 Å
- Released
- 6 Apr 2016
- Rfree
- 0.283
- Rwork
- 0.234
- Clashscore
- 9.29
- Ramachandran outliers
- 0.00%
- Rotamer outliers
- 2.42%
Crystallisation
- Technique
- Vapor Diffusion, Sitting Drop
- pH
- 4.6
- Temperature
- 292.0 K
0.16 M ammonium sulfate, 20% (w/v) PEG 4000, 20% (v/v) glycerol and 0.08 M sodium acetate, pH 4.6
What is new
No UniProt accession is mapped to this entry, so there is no target timeline.
What it led to
No case written yet for this entry.
Primary citation
Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
Immunity 2016
Do it yourself
Field Guide: Xray and crystallisation
Unlocking Membrane Protein Structures: The Crystallization Revolution Reshaping Drug Discovery
Engineering Protein Stability: Unlocking the Secrets of Successful Crystallization
AXIS: Closing the Loop on Crystal Detection
Playbook
The Self-Driving Lab: How Automation and AI Are Redefining the Pace of Discovery
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