5CD5: Crystal structure of an immature VRC01-class antibody DRVIA7 from a Chinese donor bound to clade A/E HIV-1 gp120 core
X-ray · 3.40 Å · released 6 Apr 2016 · Homo sapiens; Human immunodeficiency virus 1
Ligand: NAG
How it was solved
- Method
- X-ray
- Resolution
- 3.40 Å
- Released
- 6 Apr 2016
- Rfree
- 0.306
- Rwork
- 0.253
- Clashscore
- 7.91
- Ramachandran outliers
- 0.00%
- Rotamer outliers
- 1.47%
Crystallisation
- Technique
- Vapor Diffusion, Sitting Drop
- Temperature
- 289.0 K
0.2 M potassium iodide and 20% (w/v) PEG 3350
What it led to
No case written yet for this entry.
Primary citation
Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor
Immunity 2016
Do it yourself
Field Guide: Xray and crystallisation
Unlocking Membrane Protein Structures: The Crystallization Revolution Reshaping Drug Discovery
Engineering Protein Stability: Unlocking the Secrets of Successful Crystallization
AXIS: Closing the Loop on Crystal Detection
Playbook
The Self-Driving Lab: How Automation and AI Are Redefining the Pace of Discovery
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