6BD4: Crystal structure of human apo-Frizzled4 receptor
X-ray · 2.40 Å · released 22 Aug 2018 · Clostridium pasteurianum; Homo sapiens
Related entries for the same target
same UniProt accessionLigands: OLC, OLA, UNX
How it was solved
- Method
- X-ray
- Resolution
- 2.40 Å
- Released
- 22 Aug 2018
- Rfree
- 0.233
- Rwork
- 0.210
- Clashscore
- 7.55
- Ramachandran outliers
- 0.00%
- Rotamer outliers
- 3.12%
Crystallisation
- Technique
- Lipidic Cubic Phase
- pH
- 6.0
- Temperature
- 293.0 K
100 mM sodium cacodylate trihydrate (pH 6.0), 80 mM Magnesium Sulfate, 30% PEG400, 1.5-2.5% v/v (+/-)-2-Methyl-2,4-pentanediol
What is new
What it led to
2013 – Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Casebook · 11 Aug 2025
Do it yourself
Field Guide: Xray and crystallisation
Unlocking Membrane Protein Structures: The Crystallization Revolution Reshaping Drug Discovery
Engineering Protein Stability: Unlocking the Secrets of Successful Crystallization
AXIS: Closing the Loop on Crystal Detection
Playbook
The Self-Driving Lab: How Automation and AI Are Redefining the Pace of Discovery
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