1IOT: STABILIZATION OF HEN EGG WHITE LYSOZYME BY A CAVITY-FILLING MUTATION
X-ray · 1.75 Å · released 11 Apr 2001 · Gallus gallus
How it was solved
- Method
- X-ray
- Resolution
- 1.75 Å
- Released
- 11 Apr 2001
- Clashscore
- 6.12
- Ramachandran outliers
- 0.00%
- Rotamer outliers
- 0.00%
Crystallisation
- Technique
- Vapor Diffusion, Hanging Drop
- pH
- 4.7
- Temperature
- 296.0 K
NaCl, Na-acetete, pH 4.7, VAPOR DIFFUSION, HANGING DROP, temperature 296K
What it led to
CODSWALLOP: Every PDB entry for a protein family: what was made, what it bound, what crystallised
Playbook · 15 Sep 2026
Do it yourself
Field Guide: Xray and crystallisation
Unlocking Membrane Protein Structures: The Crystallization Revolution Reshaping Drug Discovery
Engineering Protein Stability: Unlocking the Secrets of Successful Crystallization
AXIS: Closing the Loop on Crystal Detection
Playbook
The Self-Driving Lab: How Automation and AI Are Redefining the Pace of Discovery
Tools
GOBSMACKED ↗
fold, dock, relax and annotate a protein-ligand complex on your own GPU, then find the crystal structure and g
CODSWALLOP ↗
every PDB entry for a protein family in one place: what was actually made, what it bound, what crystallised, a
TopPDBLX ↗
every crystallisation condition in the protein data bank, parsed and indexed: what worked, how often, and how
FlexAppeal ↗
Set up protein molecular dynamics without writing the script: every OpenMM option explained, a self-contained
BoltzMaker ↗
Build and analyze Boltz-2 protein structure prediction campaigns: a guided input wizard, YAML generation, and